منابع مشابه
Advances in aptamer screening and small molecule aptasensors.
It has been 20 years since aptamer and SELEX (systematic evolution of ligands by exponential enrichment) were described independently by Andrew Ellington and Larry Gold. Based on the great advantages of aptamers, there have been numerous isolated aptamers for various targets that have actively been applied as therapeutic and analytical tools. Over 2,000 papers related to aptamers or SELEX have ...
متن کاملislanding detection methods for microgrids
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15 صفحه اولConfined gold nanoparticles enhance the detection of small molecules in label-free impedance aptasensors.
A controlled architecture of nanoelectrodes, of a similar size to small molecule-binding aptamers, is synthesized inside nanoporous alumina. Gold nanoparticles with a controlled size (about 2 nm) are electrogenerated in the alumina cavities, showing a fast electron transfer process toward ferrocyanide. These uncapped nanoparticles are easily modified with a thiol-containing aptamer for label-fr...
متن کاملNicking enzyme based homogeneous aptasensors for amplification detection of protein.
A simple and highly sensitive homogeneous aptasensor is developed, which relies on nicking enzyme. The sensitivity of this newly proposed aptasensor is about three orders of magnitude higher than that of traditional homogeneous aptasensors. Furthermore, it is capable of detecting target protein in real samples.
متن کاملVoltammetric aptasensors for protein disease biomarkers detection: A review.
An electrochemical aptasensor is a compact analytical device where the bioreceptor (aptamer) is coupled to a transducer surface to convert a biological interaction into a measurable signal (current) that can be easily processed, recorded and displayed. Since the discovery of the Systematic Evolution of Ligands by Enrichment (SELEX) methodology, the selection of aptamers and their application as...
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ژورنال
عنوان ژورنال: Zeitschrift für Naturforschung B
سال: 2012
ISSN: 1865-7117,0932-0776
DOI: 10.5560/znb.2012-0147